Methodology

Methodology

Methodology Guidelines

The primary objective of EUnetHTA Methdological guidelines is to focus on methdological challenges that are encountered by HTA assessors while performing relative effectiveness assessments of pharmaceuticals or non-pharmaceutical health technologies.

The guidelines represent a consolidated view of non-binding recommendations of EUnetHTA network members and in no case are an official opinion of the participating institutions or individuals.

Guidelines in italics = under revision

Title
Version
Last Update
Link
Comparators & Comparisons: Criteria for the choice of the most appropriate comparator(s)
2.0
2015
PDF Version
Comparators & Comparisons: Direct and indirect comparisons
2.0
2015
PDF Version
Endpoints used for Relative Effectiveness Assessment Health: related quality of life and utility measures
2.0
2015
PDF Version
Endpoints used for Relative Effectiveness Assessment: Clinical Endpoints
2.0
2015
PDF Version
Endpoints used for Relative Effectiveness Assessment: Composite endpoints
2.0
2015
PDF Version
Endpoints used in Relative Effectiveness Assessment: Safety
2.0
2015
PDF Version
Endpoints used in Relative Effectiveness Assessment: Surrogate Endpoints
2.0
2015
PDF Version
Internal validity of non-randomised studies (NRS) on interventions
1.0
2015
PDF Version
Internal validity of randomised controlled trials
2.0
2015
PDF Version
Levels of Evidence – Applicability of evidence for the context of a relative effectiveness assessment
2.0
2015
PDF Version
Meta-analysis of diagnostic test accuracy studies
1.0
2014
PDF Version
Methods for health economic evaluations – A guideline based on current practices in Europe
1.0
2015
PDF Version
Personalised Medicine and Co-Dependent Technologies
1.0
2015
PDF Version
Practical considerations when critically assessing economic evaluations. Guidance document
1.0
2020
PDF Version
Process of information retrieval for systematic reviews and health technology assessments on clinical effectiveness
2.0
2019
PDF Version
Therapeutic medical devices
1.0
2015
PDF Version

Guidelines under development

Title
Status
Planned publication
Critical assessment of clinical evaluations
Concept
2020

The production of the EUnetHTA Guidelines has been successfully coordinated by EUnetHTA JA1 WP5 (HAS), EUnetHTA JA2 WP7 SG3 (IQWiG) and EUnetHTA JA3 WP6B (KCE).

If you wish to provide feedback on an existing EUnetHTA Methodological Guideline, please make use of the below template:

 

PLEG guidance

The following documentation has been produced during JA1 and JA2, as outputs of EUnetHTA JA1 and JA2 WP7, under the coordination of HAS.

Position Paper on research recommendations for AEG

Position Paper on study design for AEG

Core Protocol Pilot for AEG

Selection Prioritisation Criteria for AEG

EUnetHTA JA2 Methodology Archive (2012 – 2015)

EUnetHTA JA Methodology Archive (2010 – 2012)

This website uses cookies to ensure you get the best experience on our website. By using the website you agree to our Privacy Policy and our Terms of Use.