This document is one of two WP7 SG2 methodological documents aiming to help HTA authors/systematic reviewers in defining their recommendations for Additional Evidence Generation (AEG).
It is focusing on providing a structured approach for the identification of research gaps and improving the presentation of research recommendations arising from HTA reports. Both uncertainties related to the safety and clinical effectiveness of a health technology (answerable with biomedical research) and uncertainties related to the effective adoption and implementation of a health technology in real world practice (answerable with post-adoption surveillance and data gathering) are addressed in the paper.
The paper does not address prioritization of health technologies that should undergo an HTA process, nor prioritization of research recommendations between different intended uses of a technology or between technologies competing for health systems’ resources.
